Illumina reported first quarter 2025 Core Illumina revenue of $1.04 billion, a 1% decrease year-over-year. GAAP diluted EPS was $0.82 and non-GAAP diluted EPS was $0.97. The company updated its full-year 2025 financial guidance, reflecting anticipated impacts from geopolitical developments and tariffs, particularly affecting the Greater China region.
Core Illumina revenue for Q1 2025 was $1.04 billion, a 1% decrease compared to Q1 2024.
GAAP diluted EPS for Q1 2025 was $0.82, and non-GAAP diluted EPS was $0.97.
GAAP operating margin was 15.8% and non-GAAP operating margin was 20.4% for the first quarter of 2025.
Free cash flow for Q1 2025 was $208 million, and the company held $1.11 billion in cash and cash equivalents.
For fiscal year 2025, Illumina expects Core Illumina revenue to decline between 1% and 3% on a constant currency basis. Non-GAAP operating margin is anticipated to be approximately 21.5% - 22.0%, and non-GAAP diluted EPS is projected in the range of $4.20 - $4.30, reflecting the impact of tariffs and changes in the Greater China region.
Visualization of income flow from segment revenue to net income