Dec 31, 2024

Inovio Q4 2024 Earnings Report

Inovio reported its fourth-quarter results with modest revenue and a narrowed net loss compared to the prior year, while advancing its clinical and regulatory milestones.

Key Takeaways

Inovio generated $117,000 in revenue in Q4 2024, a slight increase from the previous year. The company reported a net loss of $19.4 million for the quarter and continued its progress toward BLA submission and future clinical trials, while maintaining sufficient cash reserves.

Q4 revenue was $117,000, up from $103,000 year-over-year.

Net loss narrowed to $19.4 million compared to $25.0 million in Q4 2023.

Operating expenses decreased to $20.5 million from $27.5 million in the same period last year.

Cash, cash equivalents, and short-term investments totaled $94.1 million as of December 31, 2024.

Total Revenue
$117K
Previous year: $103K
+14.0%
EPS
-$0.65
Previous year: -$1.1
-40.9%
Common shares outstanding
36.1M
Cash and Equivalents
$65.8M
Previous year: $145M
-54.7%

Inovio

Inovio

Inovio Revenue by Segment

Forward Guidance

Inovio expects to initiate its BLA rolling submission for INO-3107 in mid-2025 and continue advancing its clinical programs across various indications.

Positive Outlook

  • BLA rolling submission for INO-3107 expected to start mid-2025.
  • Promising interim results from DMAb technology trials showing sustained antibody production.
  • Phase 3 trial preparation underway for INO-3112 in combination with LOQTORZI.
  • Cash resources projected to support operations into Q1 2026.
  • Continued strategic collaborations and potential for additional pipeline advancements.

Challenges Ahead

  • Ongoing operational net losses projected.
  • R&D expenses continue to pressure cash burn rates.
  • Potential regulatory and trial delays may impact timelines.
  • Competition in the DNA medicine and antibody space remains strong.
  • Market conditions and future capital raising needs may present financial risks.