Dec 31, 2024
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Pharvaris Q4 2024 Earnings Report

Pharvaris reported a net loss in Q4 2024 as it continued advancing its clinical programs, with no reported revenue and increased R&D expenses.

Key Takeaways

Pharvaris ended Q4 2024 with a net loss of €34.8M and zero revenue, reflecting ongoing investment in clinical trials. The company maintained a strong liquidity position with €281M in cash and cash equivalents.

Reported net loss of €34.8M with EPS of -€0.64

Revenue remained at €0 as the company continues in clinical stages

R&D expenses increased significantly to support late-stage trials

Cash position remained strong at €281M at quarter-end

Total Revenue
€0
0
EPS
-€0.635
Previous year: -€0.724
-12.3%
R&D Expenses
€31.2M
G&A Expenses
€13.9M
Cash and Equivalents
€281M
Previous year: €391M
-28.2%

Pharvaris

Pharvaris

Forward Guidance

Pharvaris expects continued progress in its Phase 3 clinical programs with topline data for CHAPTER-3 anticipated in the second half of 2026.

Positive Outlook

  • Target enrollment completed for RAPIDe-3 Phase 3 trial
  • Enrollment underway for CHAPTER-3 Phase 3 prophylaxis trial
  • Strong cash position supports ongoing development
  • Orphan drug designation granted by European Commission
  • Long-term data reinforces clinical potential of deucrictibant

Challenges Ahead

  • No revenue generation as development-stage company
  • Net losses expected to continue due to high R&D spend
  • Regulatory approvals still pending
  • Dependence on successful trial outcomes
  • Market launch timelines extend into future years