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Dec 28, 2025
Quidel Q4 2025 Earnings Report
QuidelOrtho reported its fourth quarter and full-year 2025 financial results, with a focus on diversified diagnostics business and cost-savings initiatives.
Key Takeaways
QuidelOrtho reported total revenue of $724 million for Q4 2025, with non-respiratory revenue growing 7% in constant currency and Labs revenue growing 8%. The company achieved an adjusted EBITDA margin of 21% and adjusted diluted EPS of $0.46. For the full year 2025, total revenue was $2.73 billion, with an adjusted EBITDA of $597 million.
Total revenue for Q4 2025 was $724 million, showing a 2.2% increase compared to the prior year.
Non-respiratory revenue, excluding Donor Screening, grew 7% in constant currency for Q4 2025.
Labs revenue increased by 8% as reported and 7% in constant currency during Q4 2025.
Adjusted diluted EPS for Q4 2025 was $0.46, with an adjusted EBITDA margin of 21%.
Revenue by Segment
Revenue by Geographic Location
Forward Guidance
QuidelOrtho provided fiscal year 2026 financial guidance, projecting total revenues between $2.7 billion and $2.9 billion, adjusted EBITDA between $630 million and $670 million, and adjusted diluted EPS between $2.00 and $2.42. Free cash flow is expected to improve significantly, ranging from $120 million to $160 million.
Positive Outlook
- Total revenues are projected to be between $2.7 billion and $2.9 billion for FY 2026.
- Adjusted EBITDA is expected to be in the range of $630 million to $670 million for FY 2026.
- Adjusted EBITDA margin is projected to increase to 23.3% in FY 2026.
- Adjusted diluted EPS is expected to be between $2.00 and $2.42 for FY 2026.
- Free cash flow is anticipated to improve significantly, ranging from $120 million to $160 million in FY 2026.
Challenges Ahead
- The company did not provide a reconciliation of forward-looking non-GAAP measures to GAAP measures due to inherent difficulties in forecasting certain items.
- The guidance assumes foreign currency exchange will be neutral to full-year 2026 revenue, which could be subject to change.
Historical Earnings Impact
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Avg. Return Before/After Earnings
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