•
Dec 31, 2021

VYNE Q4 2021 Earnings Report

Reported year-end financial results and provided a corporate update.

Key Takeaways

VYNE Therapeutics reported financial results for the fourth quarter and year ended December 31, 2021. The company focused on developing novel therapies for immuno-inflammatory conditions and completed the divestiture of their topical minocycline MST franchise.

Completed the divestiture of topical minocycline MST franchise in January.

Reported positive Phase 1b safety data for FMX114.

Released promising preclinical data for InhiBET inhibitor platform.

Plan to report Phase 2a safety and efficacy results in the second quarter.

Total Revenue
$2.29M
Previous year: $4.29M
-46.5%
EPS
-$3.6
Previous year: -$7.74
-53.5%
Gross Profit
$1.39M
Previous year: $3.75M
-63.0%
Cash and Equivalents
$42.3M
Previous year: $57.6M
-26.6%
Free Cash Flow
-$10M
Previous year: -$25.4M
-60.5%
Total Assets
$67M
Previous year: $93.7M
-28.5%

VYNE

VYNE

Forward Guidance

VYNE plans to report Phase 2a safety and efficacy results in the second quarter, initiate their first in-human clinical study for VYN201 in the second half of the year, followed by exercising of the option and an IND filing for VYN202.