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Dec 27, 2025
Charles River Labs Q4 2025 Earnings Report
Charles River Labs reported slightly lower revenue in Q4 2025 and a significant GAAP net loss driven by impairment charges, while non-GAAP profitability declined modestly.
Key Takeaways
In Q4 2025, Charles River generated $994227000 in revenue, down 0.8% year-over-year. The company reported a GAAP net loss of $276555000 and operating loss of $283440000, primarily due to intangible asset and goodwill impairments, while non-GAAP EPS was $2.39.
Revenue declined 0.8% year-over-year to $994227000.
GAAP operating margin was (28.5)% due to significant impairment charges.
GAAP net loss available to common shareholders was $276555000.
Non-GAAP operating margin was 18.1% and non-GAAP EPS was $2.39.
Revenue by Segment
Forward Guidance
For 2026, Charles River expects reported revenue growth of at least flat to +1.5%, organic revenue between (1.0)% and at least flat, GAAP EPS of $6.30 to $6.80, and non-GAAP EPS of $10.70 to $11.20.
Positive Outlook
- Organic revenue expected to return to growth in the second half of 2026.
- Manufacturing segment expected to grow organically in 2026.
- Non-GAAP EPS projected to increase 4% to 9%.
- Incremental cost savings from restructuring and efficiency initiatives.
- Lower expected tax rate contributing to EPS growth.
Challenges Ahead
- Organic revenue for 2026 expected between (1.0)% and at least flat.
- Planned divestitures representing approximately 7% of annual revenue remain embedded in guidance.
- Foreign exchange expected to have a (1.0)% to (1.5)% unfavorable impact.
- Lower expected RMS revenue due to large model and Insourcing Solutions declines.
Historical Earnings Impact
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Avg. Return Before/After Earnings
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