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Dec 31, 2025
IQVIA Q4 2025 Earnings Report
IQVIA reported strong fourth-quarter and full-year 2025 results, with significant revenue and EPS growth, and issued full-year 2026 guidance.
Key Takeaways
IQVIA closed 2025 with strong performance across all segments, delivering near double-digit revenue and EPS growth. The company reported fourth-quarter revenue of $4,364 million and GAAP diluted EPS of $2.99. R&D Solutions saw its strongest quarter for net bookings, and both commercial and clinical businesses experienced strong topline growth. The company also provided optimistic full-year 2026 guidance.
Fourth-quarter revenue reached $4,364 million, an increase of 10.3% on a reported basis compared to the fourth quarter of 2024.
GAAP diluted earnings per share for the fourth quarter was $2.99, up 23.6% year-over-year.
R&D Solutions quarterly bookings exceeded $2.7 billion, resulting in a book-to-bill ratio of 1.18x.
Full-year 2026 revenue guidance is projected to be between $17,150 million and $17,350 million, with adjusted diluted EPS between $12.55 and $12.85.
Revenue by Segment
Forward Guidance
For the full year 2026, IQVIA expects revenue to be between $17,150 million and $17,350 million, with Adjusted EBITDA between $3,975 million and $4,025 million, and Adjusted Diluted Earnings per Share between $12.55 and $12.85.
Positive Outlook
- Revenue guidance of $17,150 million to $17,350 million for full-year 2026.
- Adjusted EBITDA guidance of $3,975 million to $4,025 million for full-year 2026.
- Adjusted Diluted Earnings per Share guidance of $12.55 to $12.85 for full-year 2026.
- Assumes about 150 basis points of contribution from acquisitions.
- Assumes approximately 100 basis points tailwind from foreign exchange.
Challenges Ahead
- Guidance includes a step up in interest expense of approximately $80 million from annualization of financing activities completed during 2025 and expected refinancing in 2026.
- Foreign currency exchange rates as of February 4, 2026, are assumed to remain in effect for the forecast period, which could introduce volatility.
Historical Earnings Impact
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Avg. Return Before/After Earnings
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