Dec 31, 2022

Altimmune Q4 2022 Earnings Report

Financial results for Q4 2022 were announced, and a business update was provided.

Key Takeaways

Altimmune reported a net loss of $21.7 million for the three months ended December 31, 2022. The company's cash, cash equivalents, and short-term investments totaled $184.9 million as of December 31, 2022.

Altimmune had cash, cash equivalents and short-term investments totaling $184.9 million at December 31, 2022.

Revenue was negligible for the three months ended December 31, 2022 compared to $3.3 million in the same period in 2021.

Research and development expenses were $19.2 million for the three months ended December 31, 2022, compared to $20.2 million in the same period in 2021.

Net loss for the three months ended December 31, 2022 was $21.7 million, or $0.43 net loss per share, compared to a net loss of $23.9 million in the same period in 2021.

Total Revenue
-$110K
Previous year: $3.28M
-103.4%
EPS
-$0.43
Previous year: -$0.57
-24.6%
Gross Profit
-$220K
Previous year: -$17.8M
-98.8%
Cash and Equivalents
$111M
Previous year: $190M
-41.6%
Free Cash Flow
-$17.3M
Previous year: -$22.1M
-21.6%
Total Assets
$207M
Previous year: $219M
-5.5%

Altimmune

Altimmune

Forward Guidance

Altimmune anticipates key milestones for clinical assets and data readouts for HepTcell and Pemvidutide trials.

Positive Outlook

  • Interim 24-week readout from MOMENTUM Phase 2 obesity trial expected March 2023
  • Initiation of Phase 2b non-alcoholic steatohepatitis (NASH) trial expected mid-2023
  • 24-week interim analysis of approximately 160 subjects in MOMENTUM Phase 2 obesity trial expected in the second half of March 2023
  • Initiation of Phase 2b NASH trial expected mid-2023
  • Data readout is expected in the first half of 2024 after all subjects complete the 6-month course of treatment.

Challenges Ahead

  • Delays in regulatory review
  • Manufacturing and supply chain interruptions
  • Access to clinical sites, enrollment
  • Adverse effects on healthcare systems and disruption of the global economy
  • The impact of liver fat content and demographics in the Phase 1b NAFLD study on the success of future trials