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Mar 31

Axsome Q1 2025 Earnings Report

Axsome reported Q1 2025 results with strong revenue growth driven by AUVELITY, but posted a net loss due to high SG&A and R&D investments.

Key Takeaways

Axsome Therapeutics grew revenue significantly in Q1 2025, led by AUVELITY sales, but continued to report net losses amid ongoing R&D and commercialization efforts.

Total Revenue
$121M
Previous year: $75M
+62.0%
EPS
-$0.68
Previous year: -$1
-32.0%
R&D expenses
$44.8M
Previous year: $36.8M
+21.6%
SG&A expenses
$121M
Previous year: $99M
+22.0%
Total shares outstanding
49.22M
Cash and Equivalents
$301M
Previous year: $331M
-9.2%
Total Assets
$597M
Previous year: $546M
+9.3%

Axsome

Axsome

Axsome Revenue by Segment

Forward Guidance

Axsome believes current cash levels are sufficient to reach cash flow positivity, with multiple regulatory submissions and product launches planned in 2025.

Positive Outlook

  • SYMBRAVO commercial launch on track for June 2025
  • AXS-14 NDA for fibromyalgia submitted; FDA decision on acceptance expected in Q2
  • sNDA for AXS-05 in Alzheimer’s agitation planned for Q3 2025
  • NDA for AXS-12 in narcolepsy expected in 2H 2025
  • Positive Phase 3 results reported for multiple solriamfetol trials

Challenges Ahead

  • Net loss continued due to high operating expenses
  • Cash position declined slightly from previous quarter
  • SUNOSI prescriptions down 5% QoQ
  • SG&A expenses increased significantly due to pre-launch and marketing costs
  • No revenue reported for newly approved SYMBRAVO yet