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Dec 31, 2022

Caribou Biosciences Q4 2022 Earnings Report

Reported fourth quarter and full year 2022 financial results and provided a business update.

Key Takeaways

Caribou Biosciences reported financial results for the fourth quarter and full year 2022 and reviewed recent pipeline progress. The company had $317.0 million in cash, cash equivalents, and marketable securities as of December 31, 2022, and expects these funds to be sufficient to fund its current operating plan into 2025.

CB-010 ANTLER Phase 1 trial in r/r B-NHL is ongoing with an update planned for H2 2023.

CB-011 CaMMouflage Phase 1 trial in r/r MM is recruiting patients at dose level 1.

CB-012 IND-enabling studies have been initiated, with an IND submission in r/r AML planned for H2 2023.

The company had $317.0 million in cash, cash equivalents, and marketable securities as of December 31, 2022, providing a cash runway to fund the current operating plan into 2025.

Total Revenue
$3.69M
Previous year: $2.56M
+44.3%
EPS
-$0.44
Previous year: -$0.31
+41.9%
Gross Profit
$2.79M
Previous year: $2.29M
+22.0%
Cash and Equivalents
$317M
Previous year: $414M
-23.3%
Free Cash Flow
-$26.8M
Previous year: -$22.1M
+21.4%
Total Assets
$374M
Previous year: $442M
-15.5%

Caribou Biosciences

Caribou Biosciences

Forward Guidance

Caribou plans to maintain momentum by advancing two ongoing clinical trials for off-the-shelf cell therapies in patients with hematologic malignancies and preparing an IND submission for its third program, CB-012.

Positive Outlook

  • CB-010: Provide an update from the ongoing ANTLER Phase 1 trial for CB-010 in H2 2023.
  • CB-011: Provide an update on the clearance of dose levels as appropriate from the CaMMouflage Phase 1 trial for CB-011.
  • CB-012: Submit an IND application for CB-012 in H2 2023.