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Dec 31, 2020

CRISPR Therapeutics Q4 2020 Earnings Report

CRISPR Therapeutics' fourth quarter results were negatively impacted by decreased collaboration revenue, offset by R&D and G&A expenses.

Key Takeaways

CRISPR Therapeutics reported a net loss of $107.0 million for the fourth quarter of 2020, compared to a net income of $30.5 million for the fourth quarter of 2019. The company's cash, cash equivalents, and marketable securities totaled $1,690.3 million as of December 31, 2020.

More than 20 patients have been dosed with CTX001â„¢ across CLIMB-Thal-111 and CLIMB-SCD-121 to date; completion of enrollment in both trials is expected in 2021

Additional data from CTX110â„¢ trial expected to report in 2021, along with top-line data from CTX120â„¢ and CTX130â„¢

Total collaboration revenue was $0.2 million for the fourth quarter of 2020 compared to $77.0 million for fourth quarter of 2019

Net loss was $107.0 million for the fourth quarter of 2020 compared to income of $30.5 million for the fourth quarter of 2019

Total Revenue
$370K
Previous year: $77M
-99.5%
EPS
-$1.5
Previous year: $0.51
-394.1%
Gross Profit
-$82.2M
Previous year: $28.3M
-390.8%
Cash and Equivalents
$1.17B
Previous year: $944M
+23.8%
Free Cash Flow
-$87.5M
Previous year: $2.42M
-3707.7%
Total Assets
$1.83B
Previous year: $1.07B
+71.4%

CRISPR Therapeutics

CRISPR Therapeutics

CRISPR Therapeutics Revenue by Segment

Forward Guidance

CRISPR Therapeutics anticipates completing enrollment in CTX001 clinical trials, providing data updates on allogeneic CAR-T programs, bringing the large-scale manufacturing facility online, and building commercial infrastructure in 2021.

Positive Outlook

  • Complete enrollment in the CTX001 clinical trials
  • Provide data updates on our three clinical allogeneic CAR-T programs
  • Make meaningful progress in bringing our large-scale manufacturing facility online
  • Building our commercial infrastructure
  • Advance programs as we enter a new phase of growth for the company