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Dec 31, 2023

Design Therapeutics Q4 2023 Earnings Report

Design Therapeutics reported Q4 2023 financial results and outlined progress across its GeneTAC™ platform.

Key Takeaways

Design Therapeutics reported a net loss of $11.8 million for the fourth quarter of 2023. The company's cash and securities totaled $281.8 million at year-end, supporting a five-year operating runway. Progress was highlighted across the GeneTAC™ platform, including a new drug product for Friedreich Ataxia and IND clearance for Fuchs Endothelial Corneal Dystrophy.

New drug product DT-216P2 for Friedreich Ataxia (FA) shows favorable nonclinical pharmacokinetic and injection site safety profile.

IND cleared for DT-168 for treatment of Fuchs Endothelial Corneal Dystrophy (FECD), with Phase 1 development to start in 2024.

New program unveiled for Huntington’s Disease (HD) targeting reduction of mutant huntingtin with a GeneTAC™ small molecule.

Cash and securities of $281.8 million at year-end 2023 support a five-year operating runway and advancement of up to four programs to clinical proof-of-concept.

Total Revenue
$838K
EPS
-$0.21
Previous year: -$0.31
-32.3%
Gross Profit
$700K
Cash and Equivalents
$282M
Previous year: $330M
-14.7%
Free Cash Flow
-$12.8M
Previous year: -$15.4M
-16.6%
Total Assets
$290M
Previous year: $341M
-15.1%

Design Therapeutics

Design Therapeutics

Forward Guidance

Design Therapeutics expects cash to fund operating expenses through the next five years.