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Dec 31, 2021

MacroGenics Q4 2021 Earnings Report

Reported financial results for the year ended December 31, 2021 and provided an update on recent corporate progress.

Key Takeaways

MacroGenics reported its 2021 financial results, with total revenue of $77.4 million and a net loss of $202.1 million. The company's cash, cash equivalents, and marketable securities totaled $243.6 million as of December 31, 2021, which is expected to fund operations through 2023.

Initiating Phase 1 dose escalation study of MGC018 in combination with lorigerlimab in coming weeks.

Prioritizing MGD024 as lead CD3-based DART molecule targeting CD123 and discontinuing development of flotetuzumab.

Presented encouraging preclinical combinatorial anti-tumor activity with MGD024 at ASH in December.

Plans to meet with the U.S. Food and Drug Administration (FDA) to discuss the design of a potential registration-directed study of MGC018 in patients with metastatic castration-resistant prostate cancer (mCRPC).

Total Revenue
$14.1M
Previous year: $52.7M
-73.2%
EPS
-$0.95
Previous year: $0.02
-4850.0%
Gross Profit
$12.7M
Previous year: $51.7M
-75.5%
Cash and Equivalents
$244M
Previous year: $273M
-10.6%
Free Cash Flow
-$55.7M
Previous year: -$9.09M
+512.4%
Total Assets
$335M
Previous year: $379M
-11.5%

MacroGenics

MacroGenics

MacroGenics Revenue by Segment

Forward Guidance

MacroGenics anticipates that its cash, cash equivalents and marketable securities as of December 31, 2021, plus anticipated and potential collaboration payments, and product revenues should enable it to fund its operations through 2023.

Revenue & Expenses

Visualization of income flow from segment revenue to net income