Esperion delivered robust second quarter 2025 results, with total revenue increasing 12% year-over-year to $82.4 million, driven by a 42% surge in U.S. net product revenue. The company achieved its first quarter of operating income from ongoing business and expects sustainable profitability starting in Q1 2026. Key accomplishments include settlement agreements protecting intellectual property until 2040 and continued expansion of market access for its therapies.
Total revenue for Q2 2025 increased by 12% year-over-year to $82.4 million.
U.S. net product revenue grew significantly by 42% year-over-year to $40.3 million.
The company achieved its first quarter of operating income from ongoing business, reaching $15.0 million.
Settlement agreements were reached with three ANDA filers, preventing generic versions of NEXLETOL® until 2040.
Esperion reiterates its full-year 2025 operating expense guidance and now expects to achieve sustainable profitability starting in the first quarter of 2026.