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Jun 30, 2022

Insmed Q2 2022 Earnings Report

Insmed reported strong Q2 2022 financial results with ARIKAYCE achieving 44% year-over-year growth and all clinical programs progressing on track.

Key Takeaways

Insmed reported a strong second quarter in 2022, with ARIKAYCE revenue growing 44% year-over-year. The company's clinical programs are progressing as expected, and they are reiterating their guidance of at least 30% revenue growth in 2022 and cash runway into 2024.

ARIKAYCE revenue grew 44% year-over-year, driven by strong U.S. sales and launch activities in Japan.

Enrollment remains on track for the ARISE and ENCORE trials for ARIKAYCE and the Phase 3 ASPEN study for brensocatib.

Insmed plans to develop brensocatib in two new potential indications: chronic rhinosinusitis without nasal polyps (CRSsNP) and hidradenitis suppurativa (HS).

Insmed is advancing a translational medicine portfolio and anticipates filing one to two Investigational New Drug Applications per year from this portfolio.

Total Revenue
$65.2M
Previous year: $45.4M
+43.8%
EPS
-$0.8
Previous year: -$0.91
-12.1%
Gross Profit
$48.8M
Previous year: $34.5M
+41.4%
Cash and Equivalents
$416M
Previous year: $928M
-55.2%
Free Cash Flow
-$105M
Previous year: -$78.9M
+33.3%
Total Assets
$1.05B
Previous year: $1.23B
-14.3%

Insmed

Insmed

Forward Guidance

Insmed expects full-year 2022 global revenues for ARIKAYCE to increase at least 30% year-over-year from 2021 and anticipates that its cash on hand will support its ongoing business into 2024.

Positive Outlook

  • Commercialization and expansion of ARIKAYCE globally.
  • Advancement of brensocatib, including the Phase 3 ASPEN study in patients with bronchiectasis and commercial launch readiness activities.
  • Advancement of the confirmatory, frontline clinical trial program for ARIKAYCE (ARISE and ENCORE).
  • Advancement of Insmed's earlier-stage pipeline, including the Phase 2 clinical development programs for TPIP.
  • Advancement of Insmed's translational medicine efforts.