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Dec 31, 2021

Insmed Q4 2021 Earnings Report

Insmed reported financial results for Q4 2021, highlighting ARIKAYCE revenue and providing a business and pipeline update.

Key Takeaways

Insmed reported Q4 2021 total revenue of $56.1 million, compared to $41.4 million for Q4 2020. The company's cash position is expected to support ongoing programs into 2024.

ARIKAYCE total revenue was $56.1 million for Q4 2021 and $188.5 million for the full year 2021.

Insmed anticipates at least 30% year-over-year annual growth for 2022.

Enrollment timelines were provided for the Brensocatib Phase 3 ASPEN study and ARIKAYCE post-marketing studies (ARISE and ENCORE).

The company is planning to advance Brensocatib in two additional potential indications: Chronic Rhinosinusitis without Nasal Polyps (CRS) and Hidradenitis Suppurativa (HS).

Total Revenue
$56.1M
Previous year: $41.4M
+35.5%
EPS
-$0.95
Previous year: -$1
-5.0%
Gross Profit
$42.8M
Previous year: $30.6M
+40.2%
Cash and Equivalents
$717M
Previous year: $533M
+34.5%
Free Cash Flow
-$85.3M
Previous year: -$67.7M
+25.9%
Total Assets
$1.24B
Previous year: $796M
+56.2%

Insmed

Insmed

Forward Guidance

Insmed expects full-year 2022 revenues for ARIKAYCE to increase at least 30% year over year from 2021 and anticipates that its cash on hand will support its ongoing programs into 2024.

Positive Outlook

  • Commercialization and expansion of ARIKAYCE globally
  • Launch activities for ARIKAYCE in initial European countries and in Japan
  • Advancement of the frontline clinical trial program for ARIKAYCE (ARISE and ENCORE)
  • Advancement of brensocatib, including the Phase 3 ASPEN study in patients with bronchiectasis
  • Advancement of the Phase 2 clinical development programs of TPIP