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Jun 30, 2022

Optinose Q2 2022 Earnings Report

Reported an increase in XHANCE net revenue and announced positive topline results from ReOpen2.

Key Takeaways

Optinose reported a 12% increase in XHANCE net revenue for Q2 2022 compared to Q2 2021 and announced positive topline results from the ReOpen2 clinical trial, supporting a potential new indication for XHANCE as a treatment for chronic sinusitis. The company plans to submit an sNDA for XHANCE as a treatment for chronic sinusitis by the end of 2022.

XHANCE net revenue increased by 12% compared to Q2 2021.

ReOpen2 clinical trial met both of its co-primary endpoints, demonstrating statistically significant improvement in patients with chronic sinusitis treated with XHANCE.

The company plans to submit an sNDA for XHANCE as a treatment for chronic sinusitis by the end of 2022.

Full year 2022 XHANCE net revenue is expected to be between $85 to $92 million.

Total Revenue
$20.6M
Previous year: $18.4M
+12.1%
EPS
-$0.23
Previous year: -$0.44
-47.7%
Gross Profit
$18.4M
Previous year: $15.9M
+15.7%
Cash and Equivalents
$78.3M
Previous year: $93.9M
-16.6%
Free Cash Flow
-$13.1M
Previous year: -$22.5M
-41.6%
Total Assets
$123M
Previous year: $140M
-12.0%

Optinose

Optinose

Optinose Revenue by Segment

Forward Guidance

Optinose expects XHANCE net revenues for the full year of 2022 to be between $85 - $92 million and total GAAP operating expenses for 2022 to be in the range of $129 - $134 million.

Positive Outlook

  • Potential for continued XHANCE prescription and net revenue growth
  • Potential impact of filling vacant sales territories on XHANCE prescriptions
  • Impact of fall seasonality on XHANCE prescriptions
  • Impact of new clinical data showing a reduction in acute exacerbations in nasal polyp patients with XHANCE use on prescriptions
  • Potential benefits of XHANCE for the treatment of chronic sinusitis

Challenges Ahead

  • Impact of, and uncertainties caused by the COVID-19 pandemic
  • Physician and patient acceptance of XHANCE for its current and any potential future indication
  • Company’s ability to maintain adequate third-party reimbursement for XHANCE (market access)
  • Market opportunities for XHANCE may be smaller than expected
  • Company’s ability to grow XHANCE prescriptions and net revenues