Prothena reported a net loss of $45.8 million for the third quarter of 2022, with total revenue of $1.5 million. The company's cash and restricted cash position was $497.0 million as of September 30, 2022.
Net loss was $45.8 million in Q3 2022, compared to a net income of $109.2 million in Q3 2021.
Total revenue was $1.5 million in Q3 2022, primarily from collaboration revenue from BMS, compared to $139.2 million in Q3 2021.
R&D expenses totaled $39.9 million in Q3 2022, compared to $18.0 million in Q3 2021, due to higher manufacturing and personnel-related expenses.
Cash, cash equivalents, and restricted cash totaled $497.0 million as of September 30, 2022.
Prothena is updating its projected full year 2022 net cash burn from operating and investing activities, and expects it to be $108 to $120 million which includes an expected $40 million clinical milestone payment from Novo Nordisk, and expects to end the year with approximately $522 million in cash, cash equivalents, and restricted cash (midpoint).