Prothena reported a net loss of $33.2 million for the fourth quarter of 2021, compared to a net loss of $30.7 million for the fourth quarter of 2020. Total revenue for the fourth quarter of 2021 was $1.2 million, compared to $0.4 million for the fourth quarter of 2020. The company's cash and restricted cash position was $580.4 million as of December 31, 2021.
Net cash used in operating and investing activities was $22.8 million in the fourth quarter.
Quarter-end cash and restricted cash position was $580.4 million.
Reached SPA agreement with FDA for confirmatory Phase 3 study of birtamimab and initiated the study in Mayo Stage IV patients with AL amyloidosis.
Received $80 million option payment from Bristol Myers Squibb for U.S. license to PRX005.
The Company expects the full year 2022 net cash used in operating and investing activities to be $120 to $132 million, which includes an expected $40 million clinical milestone payment from Novo Nordisk and expects to end the year with approximately $454 million in cash, cash equivalents and restricted cash (midpoint).