Prothena reported a net income of $6.3 million for the fourth quarter of 2022, compared to a net loss of $33.2 million for the same period in 2021. The increase in revenue was primarily due to a $40.0 million milestone payment from Novo Nordisk and $9.9 million in BMS collaboration revenue.
Net cash used in operating and investing activities was $5.1 million in Q4 2022, with a quarter-end cash and restricted cash position of $712.6 million.
Received $40 million milestone payment from Novo Nordisk in December 2022 for advancement of NNC6019 in a Phase 2 study.
Advanced Alzheimer’s Disease portfolio, including FDA clearance for IND application and Fast Track designation for PRX012.
Strengthened leadership position in the amyloidosis community with ongoing enrollment of the confirmatory Phase 3 AFFIRM-AL study of birtamimab.
The Company expects the full year 2023 net cash used in operating and investing activities to be $213 to $229 million and expects to end the year with approximately $512 million in cash, cash equivalents and restricted cash (midpoint).