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Dec 31, 2022

Syndax Q4 2022 Earnings Report

Reported financial results for the fourth quarter and full year ended December 31, 2022 and provided a business update.

Key Takeaways

Syndax Pharmaceuticals reported its financial results for the fourth quarter and full year ended December 31, 2022. The company had cash, cash equivalents, short-term and long-term investments of $481.3 million as of December 31, 2022. Two U.S. registrational filings are expected by the end of 2023.

Topline data from AUGMENT-101 KMT2Ar patients expected in the third quarter of 2023.

Topline data from the pivotal AGAVE-201 trial on track for mid-2023.

Two U.S. registrational filings expected by the end of 2023.

The fourth quarter was marked by significant progress on the clinical, regulatory and operational fronts.

EPS
-$0.62
Previous year: $1.81
-134.3%
$31.8M
Previous year: $23.9M
+33.2%
$10.2M
Previous year: $6.93M
+47.1%
Cash and Equivalents
$481M
Previous year: $440M
+9.4%
Free Cash Flow
-$22.9M
Previous year: $101M
-122.8%
Total Assets
$497M
Previous year: $450M
+10.6%

Syndax

Syndax

Forward Guidance

For the first quarter of 2023, the Company expects research and development expenses to be $30 to $35 million and total operating expenses to be $40 to $45 million. For the full year of 2023, the Company expects research and development expenses to be $160 to $175 million and total operating expenses to be $225 to $240 million.