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Sep 30, 2023

Spyre Q3 2023 Earnings Report

Aeglea BioTherapeutics reported third quarter 2023 financial results and provided a corporate update.

Key Takeaways

Aeglea BioTherapeutics reported a net loss of $40.1 million for the third quarter of 2023, with R&D expenses totaling $24.7 million and G&A expenses totaling $8.6 million. The company's cash and cash equivalents, marketable securities, and restricted cash totaled $204.9 million as of September 30, 2023.

SPY001 is on track for an expected IND filing in the first half of 2024.

SPY002 is on track for expected IND filing in the second half of 2024.

Stockholder vote scheduled for November 21 to allow conversion of preferred stock to common stock.

Strengthened leadership team with the appointments of Scott Burrows as Chief Financial Officer and Heidy King-Jones as Chief Legal Officer and Corporate Secretary.

Total Revenue
$0
Previous year: $174K
-100.0%
EPS
-$9.34
Previous year: -$4.75
+96.6%
Gross Profit
$0
Previous year: $174K
-100.0%
Cash and Equivalents
$90.6M
Previous year: $39M
+132.4%
Free Cash Flow
-$34.6M
Previous year: -$15.1M
+129.6%
Total Assets
$207M
Previous year: $91.6M
+126.4%

Spyre

Spyre

Forward Guidance

Aeglea is advancing a pipeline of antibody therapeutics with the potential to transform the treatment of IBD. Aeglea’s approach combines novel antibody engineering, rational therapeutic combinations, and precision immunology with the goal of maximizing efficacy, safety, and convenience of treatments for IBD. The company is developing antibodies targeting α4β7, TL1A, and IL-23.