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Dec 31, 2022

Spyre Q4 2022 Earnings Report

Aeglea BioTherapeutics reported financial results for Q4 2022 and provided program updates.

Key Takeaways

Aeglea BioTherapeutics reported Q4 2022 financial results, including development fee revenues of $0.2 million and a net loss of $18.8 million. The company's cash, cash equivalents, marketable securities, and restricted cash totaled $57.3 million as of December 31, 2022, expected to fund operations into Q4 2023.

Jeffrey Goldberg appointed president and CEO.

Senior management team strengthened with appointments of chief medical officer and chief product officer.

Cash, cash equivalents, marketable securities, and restricted cash totaled $57.3 million as of December 31, 2022, expected to fund operations into Q4 2023.

Received Fast Track Designation from the FDA for Pegtarviliase in Homocystinuria.

Total Revenue
$168K
Previous year: $3.64M
-95.4%
EPS
-$4.5
Previous year: -$7.75
-41.9%
Gross Profit
$168K
Previous year: $3.64M
-95.4%
Cash and Equivalents
$34.9M
Previous year: $15.1M
+130.2%
Free Cash Flow
-$18.1M
Previous year: -$19.3M
-5.9%
Total Assets
$71.1M
Previous year: $110M
-35.3%

Spyre

Spyre

Spyre Revenue by Segment

Forward Guidance

Aeglea expects its cash, cash equivalents and marketable securities will enable it to fund its operating expenses and capital expenditure requirements into the fourth quarter of 2023.