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Sep 30, 2023

Wave Life Sciences Q3 2023 Earnings Report

Wave Life Sciences reported a net income for Q3 2023 and provided a business update.

Key Takeaways

Wave Life Sciences reported a net income of $7.3 million for the third quarter of 2023, driven by increased revenue from collaborations. The company is advancing its RNA editing and therapeutic programs, including WVE-006, WVE-N531, and WVE-003, and expanding its pipeline with a new GalNAc-siRNA INHBE program. Cash and cash equivalents were $140 million as of September 30, 2023, expected to fund operations into 2025.

Initiated RestorAATion clinical program for WVE-006, the industry’s first-ever RNA editing clinical candidate.

On track to deliver dystrophin data from the FORWARD-53 trial of WVE-N531 in 2024.

Completed enrollment in the 30 mg multi-dose cohort of SELECT-HD with clinical data expected in Q2 2024.

Presented preclinical proof-of-concept data for a new GalNAc-siRNA INHBE program for metabolic disorders.

Total Revenue
$49.2M
Previous year: $285K
+17168.1%
EPS
$0.07
Previous year: -$0.42
-116.7%
R&D Expense
$31.6M
Previous year: $27.6M
+14.7%
G&A Expense
$13.1M
Previous year: $11.6M
+13.1%
Gross Profit
$47M
Previous year: -$2.32M
-2127.2%
Cash and Equivalents
$140M
Previous year: $97M
+44.3%
Free Cash Flow
-$34.6M
Previous year: -$26.1M
+32.6%
Total Assets
$200M
Previous year: $182M
+10.1%

Wave Life Sciences

Wave Life Sciences

Forward Guidance

Wave Life Sciences anticipates several milestones, including initiating dosing for WVE-006 in Q4 2023, delivering data from FORWARD-53 in 2024, and selecting a clinical candidate for the INHBE program in Q4 2024.

Positive Outlook

  • Initiate dosing in healthy volunteers in RestorAATion clinical program in 4Q 2023
  • Deliver proof-of-mechanism data from RestorAATion clinical program in 2024
  • Initiate dosing in potentially registrational FORWARD-53 Phase 2 clinical trial in 2023
  • Deliver data from FORWARD-53 clinical trial in 2024
  • Deliver data from 30 mg multi-dose cohort with extended follow-up, along with all single-dose data, in 2Q 2024