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Dec 31, 2022

Wave Life Sciences Q4 2022 Earnings Report

Wave Life Sciences reported financial results for Q4 2022 and provided a business update.

Key Takeaways

Wave Life Sciences reported a net loss of $43.7 million in the fourth quarter of 2022. They entered into a strategic collaboration with GSK and are advancing their RNA editing and other platform capabilities.

Achieved clinical validation of PRISM platform in 2022.

Extended leadership in RNA editing and advanced WVE-006 for AATD.

Initiating Part B of WVE-N531 study in exon 53-amenable DMD.

Strategic collaboration with GSK underway.

Total Revenue
$1.24M
Previous year: $1.77M
-29.8%
EPS
-$0.47
Previous year: -$0.61
-23.0%
R&D Expense
$31.1M
G&A Expense
$13.7M
Gross Profit
-$1.26M
Previous year: -$24M
-94.8%
Cash and Equivalents
$88.5M
Previous year: $151M
-41.2%
Free Cash Flow
-$33.6M
Previous year: -$7.05M
+377.4%
Total Assets
$146M
Previous year: $207M
-29.3%

Wave Life Sciences

Wave Life Sciences

Forward Guidance

Wave anticipates several milestones in the near future.

Positive Outlook

  • Initiate dosing in Part B of WVE-N531 clinical trial in 2023
  • Deliver data from Part B in 2024
  • Submit CTAs for first-in-human study in 2H 2023
  • Deliver additional single-dose biomarker and safety clinical data in 1H 2023
  • Deliver additional single- and multi-dose biomarker and safety clinical data in 1H 2023