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Jun 30, 2021

Ionis Q2 2021 Earnings Report

Ionis reported second quarter financial results, highlighted by progress in Phase 3 milestones for multiple drugs and expansion of drug delivery capabilities.

Key Takeaways

Ionis Pharmaceuticals reported $126 million in total revenues for Q2 2021. The company is on track to achieve its 2021 revenue guidance of more than $600 million. Key milestones included the completion of dosing in the tofersen Phase 3 VALOR study and full enrollment in the eplontersen Phase 3 NEURO-TTRansform study.

Total revenues reached $126 million.

Operating expenses were $199 million on a GAAP basis.

Net loss was $81 million on a GAAP basis.

Cash and investments totaled $2.1 billion at the end of the quarter.

Total Revenue
$126M
Previous year: $146M
-13.7%
EPS
-$0.26
Previous year: -$0.23
+13.0%
Gross Profit
$123M
Previous year: $143M
-13.8%
Cash and Equivalents
$2.1B
Previous year: $2.35B
-10.6%
Free Cash Flow
-$67M
Previous year: -$53.2M
+25.9%
Total Assets
$2.5B
Previous year: $3.08B
-18.9%

Ionis

Ionis

Ionis Revenue by Segment

Forward Guidance

Ionis expects to achieve its 2021 revenue guidance of more than $600 million and anticipates increased R&D revenue in the second half of the year. The company is revising its 2021 operating expense and net loss guidance due to the license of Bicycle’s technology.

Revenue & Expenses

Visualization of income flow from segment revenue to net income