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Sep 30, 2020

Ionis Q3 2020 Earnings Report

Ionis reported third quarter 2020 financial results, highlighting the Akcea acquisition and pipeline advancements.

Key Takeaways

Ionis Pharmaceuticals reported a net loss of $31 million on a GAAP basis but achieved a net income of $5 million on a non-GAAP basis for Q3 2020. The company saw quarter-over-quarter revenue growth, driven by SPINRAZA royalties, increased product sales from TEGSEDI and WAYLIVRA, and advancements in partnered R&D programs. Ionis maintained a strong balance sheet with $2.3 billion in cash.

Acquired Akcea Therapeutics to enhance commercial strategy and pipeline value.

Advanced inhaled delivery with IONIS-ENAC-2.5Rx for pulmonary diseases.

Initiated mid-stage studies for vupanorsen in cardiovascular disease and ION541 for ALS.

Progressed five Phase 3 studies, with a sixth expected to begin by the end of the year.

Total Revenue
$160M
Previous year: $168M
-4.8%
EPS
-$0.22
Previous year: $0.18
-222.2%
Gross Profit
$157M
Previous year: $167M
-5.9%
Cash and Equivalents
$2.33B
Previous year: $248M
+839.3%
Free Cash Flow
-$22.2M
Previous year: -$28.7M
-22.8%
Total Assets
$3.1B
Previous year: $2.89B
+6.9%

Ionis

Ionis

Ionis Revenue by Segment

Forward Guidance

Ionis is maintaining its 2020 financial guidance, expecting significant revenue and earnings growth in the fourth quarter, driven by multiple revenue sources, including a $75 million payment from Pfizer for advancing vupanorsen.

Revenue & Expenses

Visualization of income flow from segment revenue to net income