Mar 31

Ultragenyx Q1 2025 Earnings Report

Reported first quarter 2025 financial results and corporate update

Key Takeaways

Ultragenyx reported total revenue of $139 million for the first quarter of 2025, representing 28% growth year-over-year. Net loss improved to $151 million, or $1.57 per share, compared to a net loss of $171 million, or $2.03 per share, in the same period last year. The company reaffirmed its full-year 2025 financial guidance.

Total revenue for Q1 2025 was $139 million, a 28% increase from Q1 2024.

Crysvita revenue in Q1 2025 was $103 million, a 25% increase from Q1 2024.

Net loss for Q1 2025 was $151 million, an improvement from a net loss of $171 million in Q1 2024.

Cash, cash equivalents, and marketable debt securities were $563 million as of March 31, 2025.

Total Revenue
$139M
Previous year: $109M
+28.0%
EPS
-$1.57
Previous year: -$2.03
-22.7%
Total Operating Expenses
$282M
Previous year: $274M
+2.9%
Research and Development
$166M
Previous year: $178M
-7.1%
Selling, General and Admin
$87.8M
Previous year: $78.2M
+12.3%
Cash and Equivalents
$563M
Previous year: $569M
-1.0%

Ultragenyx

Ultragenyx

Ultragenyx Revenue by Segment

Ultragenyx Revenue by Geographic Location

Forward Guidance

Ultragenyx reaffirmed its full-year 2025 financial guidance, expecting total revenue between $640 million and $670 million, Crysvita revenue between $460 million and $480 million, and Dojolvi revenue between $90 million and $100 million. The company anticipates a reduction in 2025 net cash used in operations compared to 2024.

Positive Outlook

  • Total revenue expected to grow approximately 14-20% compared to 2024.
  • Crysvita revenue guidance of $460 million to $480 million for 2025.
  • Dojolvi revenue guidance of $90 million to $100 million for 2025.
  • Expected reduction in 2025 net cash used in operations compared to 2024.
  • Prioritizing expense management while investing in commercial launches and Phase 3 programs.

Challenges Ahead

  • No specific negative guidance points were explicitly stated in the provided text.