Dec 31, 2021

Ultragenyx Q4 2021 Earnings Report

Ultragenyx reported Q4 2021 financial results and provided a corporate update.

Key Takeaways

Ultragenyx reported a total revenue of $83.4 million for Q4 2021. The company made significant progress across its early and late-stage clinical pipeline and is preparing for the launch of Evkeeza in Europe.

Total revenue for Q4 2021 was $83.4 million.

Crysvita revenue in Ultragenyx territories was $55.5 million, including $50.2 million in collaboration revenue in the North American profit share territory.

Dojolvi product sales were $11.8 million.

The company had a cash balance of approximately $1.0 billion at the end of 2021.

Total Revenue
$83.4M
Previous year: $91.5M
-8.9%
EPS
-$1.79
Previous year: -$0.37
+383.8%
Total Operating Expenses
$186M
Gross Profit
$83.4M
Previous year: $91.5M
-8.9%
Cash and Equivalents
$999M
Previous year: $1.21B
-17.6%
Free Cash Flow
-$70.4M
Previous year: -$84.4M
-16.6%
Total Assets
$1.52B
Previous year: $1.76B
-13.5%

Ultragenyx

Ultragenyx

Ultragenyx Revenue by Segment

Forward Guidance

Ultragenyx expects 2022 revenue for Crysvita in Ultragenyx territories to be between $250 million and $260 million and Dojolvi revenue to be between $55 million and $65 million.

Positive Outlook

  • 2022 revenue for Crysvita in Ultragenyx territories to be between $250 million and $260 million.
  • Dojolvi revenue to be between $55 million and $65 million.
  • Submission of reimbursement dossiers expected in European countries in 2022 for Evkeeza.
  • Dosing in the Pivotal Phase 2/3 Orbit study for UX143 is expected to begin in the first half of 2022.
  • Phase 3 eNH3ance study of DTX301 expected to initiate in first half of 2022.

Revenue & Expenses

Visualization of income flow from segment revenue to net income