Dec 31, 2023

UroGen Q4 2023 Earnings Report

UroGen reported Q4 2023 earnings, highlighted by JELMYTO net product revenues of $23.5 million and the initiation of a rolling NDA submission for UGN-102.

Key Takeaways

UroGen Pharma reported JELMYTO net product revenues of $23.5 million for Q4 2023, compared to $18.1 million for the same period in 2022. The company also initiated the submission of a rolling NDA to the FDA for UGN-102.

UroGen initiated submission of a rolling NDA to the FDA for UGN-102.

The company announced next-generation novel mitomycin-based RTGel formulations for LG-IR-NMIBC and LG-UTUC programs.

JELMYTO achieved net product revenues of $82.7 million in 2023, an increase of ~28% compared with 2022.

UroGen signed a restructured agreement with Pharmakon Advisors providing up to an additional $100 million credit facility.

Total Revenue
$23.5M
Previous year: $18.1M
+30.1%
EPS
-$0.72
Previous year: -$1.22
-41.0%
R&D Expenses
$11.3M
SG&A Expenses
$24.6M
Gross Profit
$21.2M
Previous year: $15.8M
+34.2%
Cash and Equivalents
$141M
Previous year: $55.4M
+155.3%
Free Cash Flow
-$13.1M
Previous year: -$21.8M
-39.8%
Total Assets
$178M
Previous year: $136M
+31.5%

UroGen

UroGen

UroGen Revenue by Segment

Forward Guidance

UroGen anticipates full year 2024 net product revenues from JELMYTO to be in the range of $95 to $102 million. The Company also expects full year 2024 operating expenses in the range of $175 to $185 million, including non-cash share-based compensation expense of $6 to $11 million, subject to market conditions. The Company also reiterates anticipated full year 2024 non-cash financing expense related to the prepaid obligation to RTW Investments in the range of $21 to $26 million.

Positive Outlook

  • Full year 2024 net product revenues from JELMYTO to be in the range of $95 to $102 million.
  • UGN-102 NDA submission is on track.
  • Potential FDA decision as early as the first quarter of 2025 for UGN-102.
  • New mitomycin-based RTGel formulations for LG-IR-NMIBC and LG-UTUC programs are being developed.
  • Restructured agreement with Pharmakon Advisors provides up to an additional $100 million credit facility.

Challenges Ahead

  • Increased discounts related to Medicare refunds for discarded drugs and 340B purchases will further impact net revenues in 2024.
  • Full year 2024 operating expenses are expected to be in the range of $175 to $185 million.
  • Non-cash financing expense related to the prepaid obligation to RTW Investments is expected to be in the range of $21 to $26 million.
  • Clinical trials may face unforeseen delays.
  • Regulatory approval may not be obtained within the expected timeframe.